OptiMesh® HA Nano

Designed to Ignite Osseointegration

The OptiMesh HA Nano technology offers a well-studied nano-thin surface treatment. This technology is designed to create an ultra-hydrophilic absorption environment that promotes rapid cellular activity and creates a 3D bioactive surface area, all intended to accelerate osseointegration and reduce potential infection risks.

A first-of-its-kind implant

OptiMesh® HA Nano

Next generation implant combining two proven technologies

OptiMesh® and OptiMesh Align™  are the first and only conforming, patient-specific expandable implants that feature HA Nano surface treatment.

OptiMesh HA Nano Designed To

Referenced effects are based on the presence of the HA Nano surface treatment as confirmed by various studies. Studies may have been performed on different base materials than OptiMesh.

HA Nano Surface Technology

HA Nano surface technology is a 20-nanometer thin surface

treatment composed of crystalline hydroxyapatite (HA)

HA Nano Features

  • Mimics natural bone structure
  • Ultra hydrophilic
  • Precisely engineered nano-roughness
  • Promotes a rapid biological response and cellular activity
  • Leverages an active, wet chemistry method, creating an ultra-bioactive surface
HA Nano surface (40.00 k x mag) web

HA Nano surface (40.00 k X mag)

Proven Technology

  • 30+ pre-clinical and clinical studies validating enhanced osseointegration and superior clinical outcomes on multiple substrates.
  • With over 2 million implantations, accelerated osseointegration has been demonstrated through biomechanical, histomorphological, and biological evaluations.

Note: Clinical studies and usage resulting from other substrates than OptiMesh.

OptiMesh woven structure web

OptiMesh mesh structure (200x magnification)

Wicking comparison shown in real time

Rapid Surface Spreading

HA Nano’s combination of high wettability and optimal surface chemistry, with precisely engineered nano-roughness, facilitates rapid bioactivity and absorption of growth factors onto the implant.

Proven Advantages

  • New bone formation in direct contact with the implant surface is more prominent in the HA Nano treated implants.

  • Osteogenic nano markers are upregulated around HA Nano indicating more active, new bone formation.

  • A positive effect on cells and bone tissue was confirmed in 13 in-vivo studies.

  • To evaluate HA Nano’s effect on osseointegration, bone-to-implant contact was evaluated through histology after 4 weeks.

Note: Clinical studies and usage resulting from other substrates than OptiMesh.

Bone to implant chart

Results show an 181% increase in bone-to-implant contact in in-vivo studies.

Early Cell Adhesion 3hr web

HA Nano promotes an environment conducive to the up-regulation of osteogenic markers which support the promotion of early cell adhesion and faster osseointegration.

Referenced effects are based on the presence of the HA Nano surface treatment as confirmed by various studies. Studies may have been performed on different base materials than OptiMesh.

*References: Documents on File

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